https://nova.newcastle.edu.au/vital/access/ /manager/Index ${session.getAttribute("locale")} 5 Diet and esophageal cancer risk in the Eastern Cape province of South Africa https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:20739 0.1). Males and females consuming green leafy vegetables 5-7 days/wk had 38% (P = 0.04) and 50% (P = 0.007) reduced odds of developing EC, respectively, compared with consumption ≤1 day/wk. A similar reduction in odds was observed with fruit consumption. Principal component factor analysis revealed 3 distinct dietary patterns. In females, high vs. low consumption of Pattern 1 (sorghum, green leafy vegetables, green legumes, fruits, meat) was inversely associated with EC development (OR = 0.54; 95% CI: 0.34-0.89), whereas for Pattern 2 (maize, wild greens-imifino, dry beans) the odds were elevated (OR = 1.67; 95% CI: 1.04-2.67). Compared with low adherence, high adherence to Pattern 3 (wheat-based products) reduced the odds by 35% for both sexes. This study provides further evidence on the role of diet in minimizing EC risk in this population.]]> Sat 24 Mar 2018 08:00:23 AEDT ]]> Tobacco and alcohol as risk factors for oesophageal cancer in a high incidence area in South Africa https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:24595 14 g of tobacco per day were observed to have over 4-times the odds of developing OC (males OR = 4.36, 95% CI 2.24-8.48; females OR = 4.56, 95% CI 1.46-14.30), with pipe smoking showing the strongest effect. Similar trends were observed for the alcohol-related variables. The quantity of ethanol consumed was the most important factor in OC development rather than any individual type of alcoholic beverage, especially in smokers. Males and females consuming >53 g of ethanol per day had approximately 5-times greater odds in comparison to non-drinkers (males OR = 4.72, 95% CI 2.64-8.41; females OR = 5.24, 95% CI 3.34-8.23) and 8.5 greater odds in those who smoked >14 g tobacco daily. The attributable fractions for smoking and alcohol consumption were 58% and 48% respectively, 64% for both factors combined. Conclusion: Tobacco and alcohol use are major risk factors for OC development in this region. Impact: This study provides evidence for further reinforcement of cessation of smoking and alcohol consumption to curb OC development.]]> Fri 01 Apr 2022 09:30:03 AEDT ]]>